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Addition of antioxidants and polyethylene glycol 4000 enhances the healing property of honey in burns.

Subrahmanyam N. Department of Surgery, Dr. Vaishampayan Memorial Medical College, India.

A prospective study was carried out in two groups of randomly allocated 84 patients with partial-thickness burns to compare the effect of honey alone with that of honey fortified with antioxidants (vitamin C and vitamin E) and polyethylene glycol. Bums treated with honey plus antioxidants and PEG, healed earlier than those treated with honey alone In this study the addition of antioxidants and PEG accelerated the healing properties of honey in burns. In patients treated with honey alone, healthy granulation tissue appeared in the majority of cases after about one week: wounds healed by day 10 in 20 patients and by day 15 in another 12 patients. Thus 32 patients (76,1%) achieved wound healing by day 15. In patients treated with honey PEG/C/E. granulation appeared by day 4 in the majority of the cases, with wounds healing within 9 days. The time taken for wound healing differed significantly between the two groups. Allergy or other side-effects were not observed in any patient in either group.  

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